Earth is under fire by Colossus, a battleship the Größe of a city. Using powerful laser cannons, it has destroyed most of Earth's defence forces, while its many troops clean up the rest of the planet. All expect for 5 warriors.

The Battletoads, who are well aware of evil forces in the galaxy, join forces with Billy and Jimmy Lee from Double Dragon to defend Earth from the deadly ship and its troops. Using a range of special moves you must fight your way through the streets into the heart of the ship and destroy it.

Five playable characters are now available – Zitz, Rash and Pimple from Battletoads, and Jimmy and Billy from Double Dragon. Each fighter has their own style, yet the gameplay remains consistent no matter whom you choose. The action is definitely more Battletoads than Double Dragon, but Rare does a fine job at connecting the two universes without making it seem forced or arbitrary.